The use of Povidone Iodine nasal spray and mouthwash during the current COVID19 pandemic

Evidence Based Medicine is the application of the best available evidence to the clinical problem at hand. We are living in a pandemic. We do not have the luxury of Randomised Controlled Trials. We do not have the luxury of prospective studies, time and resources. We use any good evidence we have, dissect it and see if it is fair and applicable. We rely on basic principles and extrapolate as necessary.

Here’s a paper that seems based on a good basic science foundation and appears to suggest a safe, cheap and readily available additional protection against the virus.

20200323 The use of Povidone Iodine nasal spray and mouthwash during the current COVID-19 pandemic Version 4.pdf

Your choice to take it up or not. You need to critique the evidence yourself.

Because of my front line exposure to examining and operating on patients whose noses and throats may be virus laden, I decided to do this simple nasal therapy.


The mixture has to be diluted. Also, ensure the betadine you’ve got is cleared for oral use/gargle. There are some preparation with phenol mix that should be avoided. Get 1 ml of Betadine (10% Providone Iodine) add 20mls of sterile water. Put the solution into a small nasal spray bottle. 2 sprays each nose, three times a day (before the morning session, right after lunch, and before reaching home). Simple, safe and may well be protective. Stings a little but that’s all.

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